郁闷症，是一种常见病，估量全球约有3.5亿名患者。患者心境郁闷，损失爱好或享用感，产生负罪感，或自尊心缺乏，睡觉和胃口紊乱，身体疲倦，注意力不易会集。
令人欣慰的是，有许多研讨标明，咖啡和咖啡摄入量的添加，与郁闷症危险下降有显着的联系。
（原文网址：https://sprudge.com/coffee-consumption-linked-with-lower-instances-of-depression-163727.html）
鉴于或许无法翻开原文网址，现将原英文附于此：
The mood enhancing effects of coffee are unquestioned. Just ask anyone—literallyanyone—who has ever had a cup of coffee in the morning about the burst of can-do productivity they feel about halfway through that first cup. You gotta ride that wave and get the majority of your work done before it wears off. But coffee may also have significant benefits on serious mental health issues as well. A new study finds that coffee drinkers are less likely to suffer from depression.
For the study, which can be found via the National Coffee Association, Harvard Medical School professor of neurology Dr. Alan Leviton performed meta-analysis of a variety of current research available on the topic and included over 300,000 participants, more than 8,000 of those experiencing depression. Dr. Leviton found that those who “consumed higher levels of coffee were at lower risk of depression than people who consumed less or no coffee,” with coffee’s “peak protective effect appeared to be among those who consumed 400 mL/day (i.e., 13 ounces).”
Of the research used in the meta-analysis, one study, performed as part of the Korean National Health and Nutrition Examination survey, found that those who drank two or more cups of coffee a day had a “32% lower prevalence of self-reported depression” than those who didn’t drink coffee at all. Another study, this one examining over 14,000 graduates at the University of Navarra in Pamplona, Spain, found that participants who consumed four or more cups daily had a “significantly lower risk” of experiencing “physician-diagnosed depression worthy of antidepressant medication.”
Though the exact mechanism(s) are unknown, Dr. Leviton suggests five possible explanations, many of which Sprudge has covered previously. Both coffee’s anti-oxidative and anti-inflammatory properties are given as potential reasons for the phenomenon. The reasons being, per the study, are that “blood levels of oxidative-stress indicators are raised in people who have a major depressive disorder,” and that “depressed people tend to have higher blood levels of inflammation-related proteins than people who are not depressed.” Other potential explanations include caffeine, which in mice “reduces the occurrence of helpless-like and motivational behaviors that are characteristic of mouse models of depression.” Coffee’s positive effects on the gut microbiome as well as the bowels are mentioned as possible factors as well.
While coffee is truly a magical elixir, it is no substitute for actual medical advice from a professional. So if you are experiencing any symptoms of depression, reach out to a medical professional. But keep drinking coffee. They aren’t mutually exclusive.
Zac Cadwalader is the managing editor at Sprudge Media Network and a staff writer based in Dallas. Read more Zac Cadwalader on Sprudge.
咖啡对心情的影响效果是毋庸置疑的。只需问问任何人，字面上任何人，谁曾在早上喝过一杯咖啡，在榜首杯咖啡喝到一半的时分，感觉自己充满了创造力呢？你有必要驾御这种心情，在它消失之前完结你的大部分作业。咖啡对严峻的精力健康问题也有很大的优点。一个新研讨发现喝咖啡的人患郁闷症的或许性较小。
关于这项研讨，咱们能够经过全国咖啡协会哈佛医学院神经病学教授艾伦·莱维顿博士对现在关于这一主题的各种研讨进行了元剖析，包含300,000多名参与者，其间8,000多人患有郁闷症。Leviton博士发现，那些“喝咖啡水平较高的人比少喝或不喝咖啡的人患郁闷症的危险更低”，咖啡的“最高维护效果似乎是那些每天喝400 mL咖啡(13盎司)的人”。
在Meta剖析中运用的研讨中，一项作为韩国国家健康与养分查询的一部分进行的研讨发现，那些每天喝两杯或两杯以上咖啡的人比那些根本不喝咖啡的人有“32%的郁闷患病率”。另一项研讨对西班牙潘普洛纳纳瓦拉大学的1.4万名毕业生进行了查询，成果发现，每天喝四杯或四杯以上的参与者体会“医师确诊为值得抗郁闷药物医治的郁闷症”的危险峻低得多。
尽管切当的机制尚不清楚，但Leviton博士提出了五种或许的解说，其间许多曾经曾提到过。咖啡的抗氧化和抗炎特性都被认为是形成这种现象的潜在原因。原因是，依据这项研讨，“患有严峻郁闷妨碍的人血液中的氧化应激目标会升高”，并且“郁闷症患者的血液中与炎症相关的蛋白质水平往往高于不郁闷的人。”其他潜在的解说包含咖啡因，在老鼠身上，咖啡因“减少了小鼠郁闷模型中相似无助和动机的行为的产生”。咖啡对肠道微生物群和肠道的积极效果也被认为是或许的要素。
尽管咖啡确实是奇特的灵丹妙药，但它不能代替专业人士的实践医疗主张。所以假如你有任何郁闷的症状，仍是要去找专业的医师。可是持续喝咖啡。它们并不彼此排挤。
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